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Question

Receptors for the posterior pituitary hormone oxytocin are present in:

A
Perimetrium
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B
Myometrium
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C
Stratum functionalis
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D
Stratum basalis
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Solution

The correct option is B Myometrium
Oxytocin is an endocrine hormone produced by the posterior lobe of the pituitary gland. It is released during and after childbirth.

For a hormone to act, it needs to bind to its specific receptor, which will be present only on the target cells. Receptors for oxytocin are present on the myometrium of uterus. Binding of oxytocin to its receptor results in the contraction of smooth muscles that causes expulsion of the foetus from the uterus through the cervix and vagina.

The uterus is the hollow organ in mammalian females responsible for implantation and growth of an embryo.
It has 3 layers- perimetrium, myometrium and endometrium.
The endometrium is the innermost layer and is further divided into stratum functionalis and stratum basalis.

Stratum functionalis lines the uterine cavity and sheds off during menstruation.
Stratum basalis is permanent and gives rise to new stratum functionalis after each menstruation.

Myometrium is the middle layer consisting of 3 layers of smooth muscle fibres. During labour and childbirth, the myometrium layer contracts in response to oxytocin to help expel the foetus from the uterus.

Perimetrium is the outermost thin layer composed of simple squamous epithelium and areolar connective tissue. It is a serous layer that partitions the uterus in the abdominal cavity.

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