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Question

Recognise the figure and choose the correct option given below.

A
None of the above
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B
a–Proinsulin, b–A–Peptide,
c–B-Peptide, d–Insulin
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C
a–A-peptide, b–Proinsulin,
c–B-Peptide, d–Insulin
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D
a–Proinsulin, b–A-Peptide,
c–Insulin, d–B-Peptide
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Solution

The correct option is D a–Proinsulin, b–A-Peptide,
c–Insulin, d–B-Peptide
Insulin hormone
In mammals including humans, insulin is synthesised as a prohormone known as proinsulin. It has to be processed to become a fully functional hormone.

‘a’ - Proinsulin (immature insulin) which has all A, B and C peptides.
‘b’ - A-peptide of human insulin
‘c’ - Mature functional insulin free of C peptide
‘d’ - B-peptide of human insulin

Final answer:
(C) a–Proinsulin, b–A-Peptide, c–Insulin, d–B-Peptide

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