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Question

Refer to the given diagrammatic representation of the mechanism of action of a protein hormone.
In which of the following options correct labelling of A, B, and C is given?

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A
A-Generation of second messenger, B-Physiological responses, C-Biochemical responses
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B
A-Activation of genes, B-Biochemical responses, C- Generation of second messenger
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C
A-Generation of second messenger, B-Biochemical responses, C-Physiological responses
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D
A-Biochemical responses, B-Activation of genes, C-Physiological responses
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Solution

The correct option is A A-Generation of second messenger, B-Biochemical responses, C-Physiological responses

Hormones which interact with membrane-bound receptors normally do not enter the target cell but generate second messengers( cyclic AMP, IP3, etc) which in turn regulate cellular metabolism in figure a.

Hormones which interact with intracellular receptors (e.g. steroid hormones, iodothyronines etc.) mostly regulate gene expression or chromosome function by the interaction of hormone- receptor complex with the genome. cumulative biochemical actions result in physiological and developmental effects.

So, the correct answer is 'A-Generation of a second messenger, B- Biochemical responses, C- Physiological responses'.


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