Question

Restriction endonucleases were discovered by

• A. Arber et al
• B. Monod et al
• C. Cech et al
• D. Altman et al

Answer 1

The correct option is A Arber et al

• Restriction endonucleases were discovered by Arber et al. They are used in genetic engineering for gene manipulation.
• It cuts DNA base pairs at specific sites. They cut the base pairs within the molecule so they are named as an endonuclease. 3000 restriction enzyme has been discovered till now.
• They are known as molecular scissors as they are used to cut a single gene from a larger piece of DNA.
• The restriction enzyme Eco RI, Bam II, and Hind Ill are used in recombinant DNA technology to produce cuts in vector and other DNA molecules to obtain chimeric DNA.
  

So, the correct answer is option B.