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Question

RNA interference was first described in

A
Caenorhabditis elegans
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B
mammalian cells
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C
prokaryotic cells
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D
viruses
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Solution

The correct option is A Caenorhabditis elegans
RNA interference induced by small interfering RNA molecules is a naturally occurring phenomenon was first discovered for the nematode Caenorhabditis elegans 1998. Three years after the initial observation of RNAi in worms, siRNA were shown to be effector molecules that trigger RNAi in mammalian cells.

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