RNA interference which is employed in making tobacco plant resistant to Meloidegyne incognita is essentially involved in preventing the process of
translation of mRNA
Several nematodes infect a wide variety of plants and animals including human beings. A nematode known as Meloidegyne incognita infects the roots of tobacco plants and reduces the production of tobacco. Thus, to prevent this infection a strategy is adopted known as RNA interface (RNAi) which takes place in all eukaryotic organisms as a method of cellular defence. This method involves silencing of mRNA due to complementary dsRNA molecule that binds to it and prevents the process of translation of mRNA.