The correct option is D is released as a result of contact of acid chyme to the duodenal mucosa
The partially digested food mixed with gastric juices that passes from the stomach to the duodenum is called chyme. Due to the presence of Hcl and other gastric juices, it is acidic in nature. Secretin is secreted by the epithelium of the duodenum in response to this acidic chyme. In the pancreas, it stimulates the release of bicarbonates into the pancreatic juice. In the liver, it stimulates the secretion of bile. In the stomach, it inhibits gastric secretion and motility.