Question

Secretion of gastric juice is controlled by

• A. enterogastrone
• B. cholecystokinin
• C. gastrin
• D. secretin

Answer 1

The correct option is C gastrin

Gastrin is secreted by the G-cells (gastrin cells) of the stomach. It is released into the pyloric region of the stomach. It acts on the gastric glands and stimulates the secretion and release of gastric juice. It also stimulates gastric motility or the movement of chyme.
Cholecystokinin (pancreozymin) is secreted by the epithelium of the entire small intestine. In the pancreas, it stimulates the release of pancreatic juice. In the gallbladder, it stimulates the release of bile.
Enterogastrone (Gastric Inhibitory Peptide or GIP) is secreted by the epithelium of the duodenum. It acts on the stomach and inhibits the secretion of gastric juice. It also inhibits gastric motility. It slows down the gastric contraction.
Secretin stimulates the release of bicarbonates into the pancreatic juice. In the liver, it stimulates the secretion of bile. In the stomach, it inhibits gastric secretion and motility.