Question

Select proper option, by matching column 1, 2 and 3

Column 1 (Common Name)	Column 2 (Roman Numerical Designation)	Column 3 (Activation product)
P- Prothrombin	x- I	I- Convertin
Q- Proconvertin	y- V	II- Fibrin
R- Fibrinogen	z- II	III- Thrombin
S- Proaccelerin	w- VII	IV- Accelerin

• A. (P - z - III), (Q - w - I), (R - y - II), (S - x - IV)
• B. (P - w - II), (Q - z - III), (R - y - IV), (S - x - I)
• C. (P - z - III), (Q - w - II), (R - x - IV), (S - y - I)
• D. (P - z - III), (Q - w - I), (R - x - II), (S - y - IV)

Answer 1

The correct option is D (P - z - III), (Q - w - I), (R - x - II), (S - y - IV)

Prothrombin is a precursor of thrombin. Inactive prothrombin is converted into active thrombin by coagulation or clotting factor X (prothrombinase). It is also called as coagulation factor II. Proconvertin is also called as coagulation factor VII. It initiates the process of coagulation along with tissue factor. Its activation product is convertin. Inactive fibrinogen is converted into active fibrin by clotting enzyme, thrombin. It is also called as coagulation factor I. Proaccelerin is also called as coagulation factor V. Inactive proaccelerin is converted to active form accelerin by enzyme thrombin.

Thus, the correct answer is option D.