Question

Select the condition and its consequence based on human digestion and absorption: Condition Consequence

A.	Parietal cell secretion blocked	I.	Smooth movement down the intestine affected
B.	Cholecystectomy	II.	Protein digestion hindered
C.	Goblet cells non-functional	III.	Proteins not hydrolyzed; decrease in RBC population
D.	Congenital absence of enterokinase	IV.	Difficulty in digestion of lipid-rich food

• A. A-II, B-I, C-IV, D-III
• B. A-III, B-IV, C-I, D-II
• C. A-III, B-I, C-IV, D-II
• D. A-II, B-IV, C-I, D-III

Answer 1

The correct option is B A-III, B-IV, C-I, D-II

The enzymes released by the pancreas are in the inctivated form. Enterokinase is an enzyme activator released by the cells of Crypts of Leiberkuhn in the intestine. It activates trypsinogen into trypsin.

Further, trypsin acts on proteins and other inactivated enzymes such as chymotrypsin, proelastase and procarboxypeptidase. So the absence of enterokinase will severly affect protein digestion.

Parietal or oxyntic cells in the stomach secrete HCl and Castle's intrinsic factor. HCl is essential for activating pepsinogen into pepsin. Pepsin helps in protein digestion. Intrinsic factor helps in the absorption of vitamin B12 which is essential for RBC production.

Goblet cells secrete mucus which helps in easy passage of food.

Cholecystectomy is removal of gall bladder which will affect digestion of lipids or fats. Gall bladder stores and concentrates bile which contains bile salts. Bile salts help in the emulsification of fats.