Question

Select the correct bases of DNA, RNA and amino acid of beta chain causing sickle cell anaemia.

	DNA	RNA	Amino acid
(A)	CAC-GUG	GAG	Glutamic acid
(B)	CAC-GTG	GUG	Valine
(C)	CTC-GAG	GUG	Valine
(D)	CTC-GAG	GUG	Glutamic acid
(E)	CAC-GTG	GAG	Valine

• A. A
• B. B
• C. C
• D. D

Answer 1

The correct option is B B

Sickle-cell anemia is caused by a point mutation in the β-globin chain of hemoglobin, causing the hydrophilic amino acid glutamic acid to be replaced with the hydrophobic amino acid valine at the sixth position. The β-globin gene is found on the short arm of chromosome 11.

So, the correct answer is 'B'.