Question

Select the correct one in reference to Wobble hypothesis.

• A. Third base of codon lacks vibrating capacity.
• B. Third base can establish H-bonds even with the non-complementary anticodon.
• C. Specificity of a anticodon is particularly determined by first two codon.
• D. Major cause of degeneracy is the first two N-bases of codon.

Answer 1

Answer: (B)

Third base can establish H-bonds even with the non-complementary anticodon.

The wobble hypothesis explains the degeneracy of codon (one amino acid can be coded by more than one codon). It explains that t-RNA containing one amino acid can bind to more than one codon which depends on the nonprecise base pairing between the third base of the codon and the first base of anticodon this explains that the third base can establish H-bonds even with the non-complementary anticodon.

So, the correct answer is 'Third base can establish H-bonds even with the non-complementary anticodonn'.