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Question

Select the correct option describing gonadotropin activity in a normal pregnant female.

A
High level of FSH and LH facilitate implantation of the embryo
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B
High level of hCG stimulates the thickening of endometrium
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C
High level of hCG stimulates the synthesis of estrogen and progesterone
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D
High level of FSH and LH stimulates the thickening of endometrium
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Solution

The correct option is B High level of hCG stimulates the thickening of endometrium

Pregnancy
The gestation period or pregnancy refers to the time from conception to birth. It is about 9 months +/- 7 days or 265 days.

Factors maintaining pregnancy
The following factors help in maintaining pregnancy:
1)The attachment of the blastula to the endometrium is called implantation. When implantation occurs, the state of pregnancy is reached.
2)The wall of the endometrium must be thickened and nourished with a lot of blood vessels for successful implantation to occur.
3)High levels of progesterone.

Role of LH in pregnancy
Luteinizing hormone is secreted by the anterior lobe of the pituitary gland. It induces ovulation and stimulates the production of progesterone by the corpus luteum. The production of progesterone that maintains pregnancy is then taken over by hCG. Therefore the level of LH is reduced in pregnant women.

Role of FSH in pregnancy
FSH helps in the formation of the Graafian follicle. Once the state of pregnancy is reached, the levels of FSH are reduced.

Role of hCG in pregnancy
In the early stages of pregnancy, hCG (secreted by the placenta) stimulates and maintains the corpus luteum that produces estrogen and progesterone. Later it secretes progesterone, thus maintaining the thickness of the endometrium for pregnancy.

Final answer
(A) High level of hCG stimulates the thickening of the endometrium


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