Question

Select the correct option:

Select the correct sequence of formation of given intermediates of Krebs' cycle.

• A. $Succinate\to Malate\to Fumarate\to OAA$
• B. $Fumarate\to Succinate\to Malate\to OAA$
• C. $Succinate\to Fumarate\to Malate\to OAA$
• D. $Malate\to Fumarate\to Succinate\to OAA$

Answer 1

Answer: (C)

$Succinate\to Fumarate\to Malate\to OAA$

In Kreb's cycle:

1. Dehydrogenation: This process converts succinate into 4 carbon fumarate with the aid of enzyme, succinate dehydrogenase, and liberates a pair of hydrogen atoms.

2. Hydration. This process changes fumarate into 4- carbon maltate in the presence of water and an enzyme furmarase.

3. Dehydrogenation: This process restores oxaloacetate by removing a pair of hydrogen atoms from maltate with the help of an enzyme maltate dehydrogenase.

So, the correct answer is 'Succinate $\to$ Fumarate $\to$Malate $\to$ OAA'.