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Monocytes are a type of white blood cells which are the largest of all leukocytes. Monocytes are amoeboid in appearance, and have non- granulated cytoplasm; the nucleus of monocytes is bilobed.
Monocytes get differentiated into macrophages when they leave the circulation and enter any of the specialized tissues. They are responsible for the detection, phagocytosis and destruction of bacteria and other harmful organisms and have large and smooth nuclei.
A natural killer cell is a type of white blood cell that has granules (small particles) and enzymes that can kill tumour cells or cells infected with a virus.
The first type of cellular barrier is neutrophil. They are also called polymorphonuclear leukocytes (PMN, PML, or PMNL) because of the varying shape of their nucleus.