Question

Select the correct option with respect to tailing.

• A. It occurs at the 5' end of the mRNA
• B. It involves addition of methyl guanosine triphosphate
• C. Tailing occurs during replication
• D. Addition of adenylate residues

Answer 1

The correct option is D Addition of adenylate residues

The hnRNA formed as a result of transcription in eukaryotes undergoes post-transcriptional changes which include capping and tailing.

Tailing is the process of addition of 200-300 adenylate residues at the 3’ end of hnRNA.

Methyl guanosine triphosphate is added to the 5’ end of hnRNA. This process is called capping. It protects the nascent RNA from being damaged by the action of various enzymes.