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Amino Acids

Select the co...

Question

Select the correct options.

A

Isoelectric point is the pH at which an amino acid exists primarily in its neutral from

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B

Isoelectric point is the average of

p K_{a}

value of

α

-

C O O H

amino

α

-

N H_{3}^{+}

groups[valid only for neutral amino acid]

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C

Glycine is characterised by two

p K_{a}

values

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D

For neutral amino acid, the concentration of zwitter ion is maximum at its isoelectric point

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Solution

The correct options are
A Isoelectric point is the pH at which an amino acid exists primarily in its neutral from
B Isoelectric point is the average of $p K_{a}$ value of $α$ - $C O O H$ amino $α$ - $N H_{3}^{+}$ groups[valid only for neutral amino acid]
C Glycine is characterised by two $p K_{a}$ values
D For neutral amino acid, the concentration of zwitter ion is maximum at its isoelectric point
The intermediate pH, at which the amino acid shows no tendency to migrate towards any of the electrodes, when placed in an electric field, is known as isoelectric point.
For neutral amino acid, the concentration of zwitter ion is maximum at its isoelectric point as net charge is zero at this point.
Glycine is characterised by two pKa values (amine and carboxylic groups).

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Similar questions

Q. Lysine is an amino acid with three ionizable group. These are the

α

α

ε

-amino group with pKa value of

2.2, 9.2

10.8

,respectively . The isoelectric point (pI) for Iysine is

Q. Using the provided

p K_{a}

values for fully protonated proline, determine an isoelectric point at which the amino acid exist mostly in its zwitter ionic form.

^{+} N H_{3} - C H (R) - C O_{2} H

K a_{1} = 10^{- 7}

. The isoelectric point of the

α

-amino acid occur at pH = 8.2 Hence

p K a_{2}

of the conjugate acid of

α

-amino acid is equal to:

+ N H_{3} - C H (R) - C O_{2} H

K a_{1} = 10^{- 7}

. The isoelectric point of the

α -

amino acid occur at

p H = 8.2

p K a_{2}

of the conjugate acid of

α -

amino acid is equal to:

In an amino acid, the carboxyl group ionizes at $p K a_{1} = 2.34$ and ammonium ion at $p K a_{2} = 9.6$ . The isoelectric point of the amino acid is at pH.

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