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Question

Select the correct statement with respect to the Krebs cycle.

A
Occurs in cytoplasm of the mitochondria in the absence of O2
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B
Favoured by coenzyme NADP+
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C
Intermediate products contain four, five and six carbon atoms
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D
Substrate molecule is a 3C compound
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Solution

The correct option is C Intermediate products contain four, five and six carbon atoms
Krebs cycle occurs in cytoplasm of mytochondria in the presence of oxygen. Acetyl-CoA which is a 2C molecule is the substrate of the cycle. Acetyl-CoA then combines with one oxaloacetate, a 4C molecule, to produce a molecule of citrate which contains six carbon atoms. Citrate is then converted to a 5C molecule,
α-keto glutarate which in turn regenerates oxaloacetate after many intermidiates. Hence, intermediate products contain four, five and six carbon atoms. The cycle is also favoured by NAD+ and FAD+.

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