Question

Select the incorrect statement regarding pedigree analysis.

• A. Solid symbols show unaffected individuals
• B. Proband is the person from which case history starts
• C. It is useful for genetic counsellors
• D. It is an analysis of traits in several generations of a family

Answer 1

The correct option is A Solid symbols show unaffected individuals

Pedigree analysis is the study and analysis of the inheritance pattern of a particular trait in several generations of a family.

In a family, the first person to receive genetic counseling and/or testing for suspected hereditary disorder is the proband. It may or may not be affected with the disease.

Solid symbols show affected individuals. Unaffected or normal individuals are represented without solid symbols. Different symbols are used in pedigree analysis as shown below.