Question

Select the option which is not correct with respect to enzyme action

• A. Substrate binds with enzyme at its active site
• B. Addition of lot of succinate does not reverse the inhibition of succinic dehydrogenase by malonate
• C. A non-competitive inhibitor binds the enzyme at a site distinct from that which binds the substrate
• D. Malonate is a competitive inhibitor of succinic dehydrogenase

Answer 1

The correct option is B Addition of lot of succinate does not reverse the inhibition of succinic dehydrogenase by malonate

The inhibition of the enzyme, succinate dehydrogenase by malonate is an example of competitive inhibition. Such inhibition is overcome by addition of excess substrate (succinate) in the medium.