Question

Select the wrong pair

• A. RNA polymerase I -Sn RNA 5S rRNA, r-RNA
• B. RNA polymerase I - r-RNA
• C. RNA polymerase II - hnRNA
• D. RNA polymerase III - tRNA

Answer 1

The correct option is A RNA polymerase I -Sn RNA 5S rRNA, r-RNA

RNA polymerase 1 (also known as Pol I) is, in higher eukaryotes, the polymerase that only transcribes ribosomal RNA (but not 5S rRNA, which is synthesized by RNA polymerase III), a type of RNA that accounts for over 50% of the total RNA synthesized in a cell.

RNA polymerase II (RNAP II and Pol II) is a multiprotein complex. It catalyzes the transcription of DNA to synthesize precursors of mRNA and most snRNA and microRNA. RNA polymerase II also transcribes hnRNA and RNA Polymerase III transcribes tRNA. Therefore option A is wrongly matched.