Question

Sickle cell anaemia is an example of

• A. Single base substitution mutation
• B. Insertion of a single base
• C. Non-frameshift mutation
• D. Deletion of a single base

Answer 1

The correct option is A Single base substitution mutation

Sickle cell anaemia is caused by the substitution of a single nucleotide in the gene sequence, which eventually leads to the replacement of the amino acid glutamic acid with valine, affecting the final protein formed.