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Sickle cell anaemia, the best example of natural selection is due to gene modification related to amino acid of
Sickle cell anaemia, the best example of natural selection is due to gene modification related to amino acid of
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Solution
The correct option is B Second β chain
Sickle cell anemia is a genetic disorder of the red blood cells (RBCs). In this disease, instead of having normal disc shape, RBCs have an abnormal crescent shape which looks like a sickle. Hemoglobin is present in red blood cells that carries oxygen. It has two α chains and two β chains. The sixth position in the second β chain has glutamic acid which is replaced with valine in sickle β chain. This occurs due to the gene modification which results in two abnormal copies of the haemoglobin gene.Thus, the correct answer is option C.
Sickle cell anemia is a genetic disorder of the red blood cells (RBCs). In this disease, instead of having normal disc shape, RBCs have an abnormal crescent shape which looks like a sickle. Hemoglobin is present in red blood cells that carries oxygen. It has two α chains and two β chains. The sixth position in the second β chain has glutamic acid which is replaced with valine in sickle β chain. This occurs due to the gene modification which results in two abnormal copies of the haemoglobin gene.
Thus, the correct answer is option C.
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