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Question

Sickle cell anemia is caused

A
When valine is replaced by glutamic acid in beta polypeptide chain
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B
When glutamic acid is replaced by valine in beta polypeptide chain
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C
When glutamic acid is replaced by valine in alpha polypeptide chain
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D
When valine is replaced by glutamic acid in alpha polypeptide chain
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Solution

The correct option is B When glutamic acid is replaced by valine in beta polypeptide chain
Sickle cell anaemia is caused when glutamic acid is replaced by valine in beta polypeptide chain.

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