The correct option is B Proteins
Particles which are lipid soluble (i.e., lipophilic or hydrophilic) can
easily diffuse through the cell membrane as the lipid is a major
constituent of the membrane. Where as hydrophilic substances (i.e., the
substances which are soluble in water, e.g., glucose) do not pass
through a biological membrane by simple diffusion. They are, therefore,
transported across a cell membrane by facilitated diffusion (i.e.,
carrier mediated diffusion), which takes place with the help of certain
transport proteins. So, the correct answer is 'Proteins'.