The correct option is D Edward Jenner
The first vaccine was developed by Edward Jenner against smallpox. Jenner had noticed that milkmaids who were exposed to cowpox virus were not affected by the smallpox virus. Inorder to test his theory, Jenner injected a small dose of cowpox virus into a boy. Once he recovered, Jenner injected the boy with smallpox virus. He observed that the boy did not get the disease. This finding led to the discovery of the smallpox vaccine.