Question

Sort the events that occur during transcription

• A. Termination
• B. Elongation
• C. Capping
• D. Initiation
• E. Poly A tailing

Answer 1

To begin transcribing a gene, RNA polymerase binds to the DNA of the gene at a region called the promoter. This process is called initiation.
Once RNA polymerase is in position at the promoter, the next step of transcription is elongation.
During elongation, RNA polymerase transcribes along one strand of DNA, known as the template strand, in the 3' to 5' direction. For each nucleotide in the template, RNA polymerase adds a complementary RNA nucleotide to the 3' end of the RNA strand.
RNA polymerase will keep transcribing until it gets signals to stop. The process of ending transcription happens when the polymerase transcribes a sequence of DNA known as a terminator and this process is called transcription termination.
The resultant RNA molecule is called a pre-mRNA. It undergoes further processing to form a mature functional RNA. These processing steps include

• Addition of a 5' cap to the beginning of the RNA (capping)
• Addition of a poly-A tail (tail of A nucleotides) to the end of the RNA (tailing)
• Addition of additional carbohydrate and fatty acid groups if required.