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Metaphase

Spindles are ...

Question

Spindles are arrested by colchicine at

A

Anaphase

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B

Metaphase

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C

Telophase

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D

Prophase

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Solution

The correct option is B Metaphase
Colchicine is an alkaloid that arrests the polymerization of the spindle fibres such that the cell is not able to switch to the anaphase. The chromosomes remain condensed and aligned to the central plate in the metaphase.
Hence, the correct answer is 'Metaphase'

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Q. Chromosomes in metaphase get arranged at the equatorial plate (see Fig. 1). When these cells are treated with colchicine, cell division is arrested and the cells never enter anaphase. If we were to compare a colchicine treated cell at metaphase and an untreated cell in the same phase, we notice that chromosomes are more dispersed and do not arrange themselves on the equatorial plate in the treated cells (see Fig 2.).
Using this information, which of the following will be affected by colchicine?

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