State the importance of different functional derivative of carboxylic acid.
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Solution
The functional group that undergo nucleophilic acyl substitutions are called carboxylic acid derivatives. These include carboxylic acid themselves, carboxylates, amides, esters, thioesters, and acyl phosphates. Two more examples of carboxylic acid derivatives which are less biologically relevant but important in laboratory synthesis are carboxylic acid anhydrides and acid chlorides.