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Question

State the role of pancreatic juice in digestion of proteins.

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Solution

Pancreatic juice contains a variety of inactive enzymes such as trypsinogen, chymotrypsinogen, and carboxypeptidases. These enzymes play an important role in the digestion of proteins.
Physiology of protein digestion
The enzyme enterokinase is secreted by the intestinal mucosa. It activates trypsinogen into trypsin.
Trypsin then activates the other enzymes of pancreatic juice such as chymotrypsinogen and carboxypeptidase.
Chymotrypsinogen is a milk-coagulating enzyme that converts proteins into peptides.
Carboxypeptidase acts on the carboxyl end of the peptide chain and helps release the last amino acids. Hence, it helps in the digestion of proteins.
Thus, in short, we can say that the partially hydrolysed proteins present in the chyme are acted upon by various proteolytic enzymes of the pancreatic juice for their complete digestion.

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