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Question

State whether true or false:
Antiretroviral drugs block the HIV-RT enzyme.

A
AIDS is an immunodeficiency disease
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B
It is cause by the retrovirus HIV
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Solution

The correct option is A AIDS is an immunodeficiency disease
AIDS (Acquired Immuno Deficiency Syndrome) is caused by HIV. This virus selectively infects and kills the T-lymphocytes. The first step post infection is the reverse transcription of RNA into DNA so that this r-DNA can get inserted into the human genome. This is brought about by a viral enzyme, known as HIV-RT, in which RT stands for reverse transcriptase. There is a class of drugs called Antiretroviral drugs (ARV) which are essentially inhibitors of this enzyme.

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