The correct option is A True
The ratio between the total amount of purines (A+G) and pyrimidines (T+C) is always 1:1. This is obviously because a purine always pairs up with a pyrimidine to form a base pair. A and T form a base pair while G and C form another pair. However, the amount of A+T need not always be equal to the amount of G+C. The ratio A+T/G+C remains constant for a particular species, but could vary from one species to another.