Question

Stratum corneum is protective barrier and first physical immune system due to the presence of _______ in mammals.

• A. Sweat glands
• B. Sebaceous glands
• C. Fatty acids and lactic acid secretions
• D. All of the above

Answer 1

The correct option is D All of the above

The physical barrier is mainly localized in the stratum corneum, which consists of protein-enriched cells and lipid-enriched intercellular domains. Any modifications in epidermal differentiation and lipid composition results in various skin alterations and diseases. Hair follicles, sebaceous glands, sweat glands, apocrine glands, and mammary glands are considered epidermal glands. The acidic quality of the skin plays an important role in combating bacterial growth. The skins acidity results from lactic acid from its own keratinocytic byproducts, amino acids from sweat, and the fatty acids from sebum.