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Question

Study the following events related to Na and K voltage-gated channels and find the correct combination:

S.No
Channel
Gate
Resting Phase
Depolarised
Hyperpolarized
RepolarisationSpeed of response
A
Na
Activation gate
Closed
Open
Open
Closed
Fast
B
Na
Inactivation gate
Open
Open
Closed
Slow

C
K
Activation gate
Closed
Closed
Open
Open
Slow

A
A
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B
B
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C
C
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D
Both A and C
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Solution

The correct option is A A
The type of gate or sodium channels in the neurons is of activaetd type. When the neuonal membrane is at resting phase, the sodium channels are closed. When there is impulse generation, there is depolarisation of the membrane which results in the opening of the sodium channels. The channels are in open state, when the neuron is in hyperpolarised state. The gates close when the membrane comes back to resting phase after repolarisation. The speed of response is very fast as there is flow of three sodium ions through the channel.
Thus, the correct answer is option A.

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