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Question

Substrate phosphorylation occurs during

A
Fumaric acid Malic acid
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B
Oxalosuccinic acid Ketoglutaric acid
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C
Succinic acid Fumaric acid
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D
Ketoglutaric acid Succinic acid
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Solution

The correct option is D Ketoglutaric acid Succinic acid
When a single round of Krebs' cycle completes, only 1 ATP/GTP is produced by substrate level phosphorylation. Ketoglutarate dehydrogenase (6C) is converted to succinyl CoA which is then converted to succinic acid (4C) by phosphorylating 1 ADP to ATP. So the answer is 'Ketoglutaric acid Succinic acid'.

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