Question

Sulpha drugs act as competitive inhibitors

• A. In folic acid synthesis in bacteria
• B. In folic acid synthesis in viruses
• C. For succinate dehydrogenase
• D. For glucose 6-phosphate

Answer 1

The correct option is A In folic acid synthesis in bacteria

Folic acid or folate is used to synthesize nucleic acid. Dihydropteridine and p-aminobenzoic acid react in the presence enzyme dihydropteroate synthase for the synthesis of folic acid in bacteria. Sulpha drugs act as a competitive inhibitor by attaching on the active site of the enzyme and thus inhibit the growth and multiplication of bacteria by inhibiting the formation folic acid.

So, the correct answer is option A.