Statement 1 is false because, the sequence number of the subsequent segments depends on the number of bytes characters in the current segment.
Statement 2 True, because RTO timer is always ≥ Estimated RTT.
Statement 3 False. Receiver window is used to give the sender and idea of how much free buffer space is available at the receiver.
Statement 4 is true , TCP is not permitted to overflow the allocated receiver buffer.
Hence when the sender cannot send any more data receiver window would be 0 and hence. The buffer would have unacknowledged data.