Question

Synthesis of leading and lagging strand require a

• A. single primer
• B. single and many primers respectively
• C. many and single primers respectively
• D. many primers

Answer 1

The correct option is B single and many primers respectively

The main difference between leading and lagging strand is that the leading strand is the DNA strand, which grows continuously during DNA replication whereas lagging strand is the DNA strand, which grows discontinuously by forming short segments known as Okazaki fragments.

The leading strand can be extended from one primer alone, whereas the lagging strand needs a new primer for each of the short Okazaki fragments.