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Question

T-cells originate in the ____________ and travel to the _____________ to mature and differentiate.

A
Thymus, bone marrow
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B
Bone marrow, thymus
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C
Bone marrow, spleen
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D
Lymph nodes, thymus
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Solution

The correct option is B Bone marrow, thymus
Lymphocytic cells are formed from the lymphoid progenitor cells present in the bone marrow, which leads to the formation of both T and B-cells. T-cells originate in the bone marrow but migrate to the thymus gland for maturation. Hence they are also called thymus-dependent lymphocytes.

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