Question

Template theory of enzyme action is supported by

• A. Enzymes occur in living beings and speed up certain reactions.
• B. Enzymes speed up reaction.
• C. Enzymes determine the direction of reaction.
• D. Compounds similar to substrate inhibit enzyme activity.

Answer 1

The correct option is D Compounds similar to substrate inhibit enzyme activity.

The mode of enzyme action was supported by two theories. They are Lock and Key Theory or Template theory given by Emil Fisher and Induced Fit Theory given by Koshland. The lock and key theory, the active sites of the enzymes have a specific geometric shape where in the substrate molecules fit in just like a key in a particular lock. It forms a temporary enzyme-substrate complex and the substrate molecules are converted to products. A temporary enzyme product complex is also formed. This theory explains competitive inhibition because the inhibitors which are similar in shape to substrate will inhibit the enzyme activity by binding to the active sites.