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B
Decreased synthesis of β-polypeptide chain of Haemoglobin.
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C
Decreased production of RBC that cause anemia.
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D
All of the above.
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Solution
The correct option is B Decreased synthesis of β-polypeptide chain of Haemoglobin. In thalassemia, there is a partial or complete deficiency in the synthesis of B-chain of the hemoglobin molecule. Therefore, the correct answer is option B.