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Question

Thalidomide is a non-barbiturate sedative drug, which was to be given to pregnant women. Its use was withdrawn in 1961, because it resulted in phocomelia. This condition illustrates


A
Early abortion of foetus
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B
Poor development of foetus
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C
Malformation of foetus
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D
Erythroblastosis foetalis
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Solution

The correct option is C Malformation of foetus
Thalidomide is used by pregnant women for morning sickness. Drug action causes peripheral neuropathy in adults and rare birth defects like phocomelia (hand plate is there but the proximal elements are absent or very short). Children showed amelia (no limbs) forelimb anomalies, hand plate anomalies and damage to ears, eyes internal organs, genitalia, and heart. So, the correct answer is option C.

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