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Question
The absolute configuration of given compound is:
The absolute configuration of given compound is:
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Solution
The correct option is A (2S, 3R)
The given compound is in Fischer projection. To assign absolut configuration priority for the group should be given according to their atomic number/mass (CIP rule).
The absolute configuration of given compound is (2S, 3R).
(2S, 3R)-3-chloro-2-hydroxybutanoic acid.
CIP rule:
1. The atom (directly attached to chiral atom) with higher atomic number will be prioritised.
2. In case of isotopes, heavier isotope will be assigned higher priority.
3. If a group of atoms is attached and first atom is common in two or more groups, then go for second or third atom and so on till the first point of difference.
4. Groups containing double or triple bonds between atoms are considered as if both atoms were duplicated or triplicated
The given compound is in Fischer projection. To assign absolut configuration priority for the group should be given according to their atomic number/mass (CIP rule).
The absolute configuration of given compound is (2S, 3R).
(2S, 3R)-3-chloro-2-hydroxybutanoic acid.
CIP rule:
1. The atom (directly attached to chiral atom) with higher atomic number will be prioritised.
2. In case of isotopes, heavier isotope will be assigned higher priority.
3. If a group of atoms is attached and first atom is common in two or more groups, then go for second or third atom and so on till the first point of difference.
4. Groups containing double or triple bonds between atoms are considered as if both atoms were duplicated or triplicated
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