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Question

The active form of Entamoeba histolytica feeds upon

A
Food in intestine.
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B
Blood only.
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C
Erythrocytes; mucosa and submucosa of colon.
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D
Mucosa and submucosa of colon only.
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Solution

The correct option is D Erythrocytes; mucosa and submucosa of colon.
Entamoeba histolytica is a protozoan parasite responsible for a disease called amoebiasis. It occurs usually in the large intestine and causes internal inflammation. The life cycle of Entamoeba histolytica does not require any intermediate host. Mature cysts (spherical, 1215 m in diameter) are passed in the feces of an infected human. Another human can get infected by ingesting them in fecally contaminated water, food or hands. If the cysts survive the acidic stomach, they transform back into trophozoites in the small intestine. Trophozoites migrate to the large intestine, where they live and multiply by binary fission. Both cysts and trophozoites are sometimes present in the feces. Cysts are usually found in firm stool, whereas trophozoites are found in loose stool. Only cysts can survive longer periods (up to many weeks outside the host) and infect other humans. If trophozoites are ingested, they are killed by the gastric acid of the stomach. Occasionally trophozoites might be transmitted during sexual intercourse. Damage is caused by the lysis of epithelial cells, due in part to the insertion of pore-forming proteins into the membrane of the cell. Neutrophils and non-activated macrophages may also be killed and ingested by the organism, limiting the ability of the immune system to deal with the disease. E. histolytica is also capable of phagocytosing red blood cells. They feed up on erythrocytes, mucosa and submucosa of colon.

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