Question

The active site of an enzyme is formed by a few of the enzyme's

• A. Carboxyl groups of the amino acids in $1^0$ and $2^0$ structure
• B. Amino groups of the amino acids in $1^0$ and $2^0$ structure
• C. R groups of the amino acids in $3^0$ structure
• D. Exposed sulphur bonds in $1^0$ and $3^0$ structure

Answer 1

The correct option is C R groups of the amino acids in $3^0$ structure

• The active sites of the enzyme are formed by the amino acids which are present in the structure. These are special sites that catalyze reactions with the help of special arrangement of the R groups of amino acids in the tertiary structure.
• The interactions taking place between the side chains of amino acids give catalytic activity to the enzyme.

The carboxyl group and the amino group of the proteins help it in folding rather than much activity as an active site.

• The primary and secondary structures of proteins usually do not have enzymatic activity and they need to fold in a special tertiary confirmation to become enzymatic.

So the correct answer is ' R groups of the amino acid in 3° structure'.