Question

The anterior pituitary gland facilitates growth of an individual by release of the human growth hormone (HGH) which in turn in regulated by two hormones namely growth hormone releasing hormone(GHRH) and growth hormone inhibiting hormone(GHIH). Imbalance of these hormones could result in gigantism, dwarfism or acromegaly. Interpret the data given and select the appropriate statement.

Individual	Age group	Hormones released
$1$	$2-5$yrs	Excessive GHRH
$2$	$2-5$yrs	Normal GHRH
$3$	$30-35$yrs	Excessive GHRH
$4$	$30-35$yrs	Excessive GHIH
$5$	$2-5$yrs	Excessive GHIH

• A. $1$ and $3$ will lead to gigantism while $4$ and $5$ will show dwarfism
• B. $3$ will show gigantism, $1$ will show acromegaly and $4$ and $5$ will show dwarfism
• C. $2,3$ and $4$ will show normal growth
• D. $1$ will show gigantism, $3$ will show acromegaly and $5$ will show dwarfism

Answer 1

The correct option is D $1$ will show gigantism, $3$ will show acromegaly and $5$ will show dwarfism

Growth hormone(GH) stimulates body growth by promoting the synthesis and deposition of proteins in tissues and growth of bones and muscles. It deficient secretion at an early stage causes dwarfism while its excessive secretion from childhood causes gigantism. Its over-secretion in adulthood produces acromegaly.