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Question
The antibody which can cross placental barrier is
The antibody which can cross placental barrier is
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Solution
The correct option is D IgG
Antibodies or immunoglobulins are proteins produced by the B-lymphocytes (white blood cells with non-granular cytoplasm that originate and mature in the bone marrow) that are present in the blood and lymph. They provide immunity against specific antigens (foreign substances that can trigger production of antibodies and immunological cells).
Five different classes of antibodies are produced in the body, namely, IgA, IgG, IgM, IgE and IgD.
‘Ig’ here stands for immunoglobulin. IgG is the only maternal immunoglobulin that can cross the placenta and provides immunity to the foetus.
IgG is the most abundant class of immunoglobulins in the body constituting 75% of all of them.
IgA, IgE and IgM are unable to pass through the placental barrier. The placental barrier allows the movement of only IgG antibodies across it because of the presence of special receptors on the placenta that can recognize the IgG antibodies and allow their movement.
IgA is known as the secretory immunoglobulin and is found in secretions of the body including the mother’s milk or colostrum.
IgE triggers allergic responses on contact with antigens.
IgM is the largest of the five classes of antibodies but is found in small amounts in the body. It is the first antibody to attack antigens. It possesses ten antigen binding sites which can attach to the antigens.
Antibodies or immunoglobulins are proteins produced by the B-lymphocytes (white blood cells with non-granular cytoplasm that originate and mature in the bone marrow) that are present in the blood and lymph. They provide immunity against specific antigens (foreign substances that can trigger production of antibodies and immunological cells).
Five different classes of antibodies are produced in the body, namely, IgA, IgG, IgM, IgE and IgD.
‘Ig’ here stands for immunoglobulin. IgG is the only maternal immunoglobulin that can cross the placenta and provides immunity to the foetus.
IgG is the most abundant class of immunoglobulins in the body constituting 75% of all of them.
IgA, IgE and IgM are unable to pass through the placental barrier. The placental barrier allows the movement of only IgG antibodies across it because of the presence of special receptors on the placenta that can recognize the IgG antibodies and allow their movement.
IgA is known as the secretory immunoglobulin and is found in secretions of the body including the mother’s milk or colostrum.
IgE triggers allergic responses on contact with antigens.
IgM is the largest of the five classes of antibodies but is found in small amounts in the body. It is the first antibody to attack antigens. It possesses ten antigen binding sites which can attach to the antigens.
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