Question

The appearance of albumin in the urine is most likely due to -

• A. Damage to the proximal convoluted tubules
• B. Damage to the Malpighian corpuscles
• C. Decrease in the blood osmotic pressure
• D. Increase in the blood pressure

Answer 1

The correct option is B Damage to the Malpighian corpuscles

Glomerulus along with Bowman’s capsule, is called the Malpighian body or renal corpuscle.
The epithelial cells of Bowman’s capsule called podocytes are arranged in an intricate manner so as to leave some minute spaces called filtration slits or slit pores. Blood is filtered so finely through these membranes that almost all the constituents of the plasma except the proteins pass onto the lumen of the Bowman’s capsule.

Hence, the damage to Malpighian corpuscle will leads to passing of protein (albumin) through the membrane.