1
Question
The ‘beads on string’ structure which seen under EM are
The ‘beads on string’ structure which seen under EM are
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Solution
The correct option is A Nucleosome
Histone octamer
Histones are positively charged proteins rich in basic amino acids such as lysine and arginine. 8 histone proteins form a core around which the negatively charged DNA strand is wound to form a nucleosome structure.
Nucleosome
Nucleosomes are submicroscopic units of chromatin which are about 11nm in diameter and 5.7-6 nm in height. Each nucleosome consists of a core of 8 histone molecules around which the DNA strand is tightly wrapped in 2 circles. Adjacent nucleosomes are connected by a linker DNA. A typical nucleosome consists of 200 base pairs of DNA. Nucleosomes on DNA form a ‘beads on string’ appearance, where the nucleosome forms the beads and the linker DNA is seen as the string.
Final answer
(B) Nucleosome
Histone octamer
Histones are positively charged proteins rich in basic amino acids such as lysine and arginine. 8 histone proteins form a core around which the negatively charged DNA strand is wound to form a nucleosome structure.
Nucleosome
Nucleosomes are submicroscopic units of chromatin which are about 11nm in diameter and 5.7-6 nm in height. Each nucleosome consists of a core of 8 histone molecules around which the DNA strand is tightly wrapped in 2 circles. Adjacent nucleosomes are connected by a linker DNA. A typical nucleosome consists of 200 base pairs of DNA. Nucleosomes on DNA form a ‘beads on string’ appearance, where the nucleosome forms the beads and the linker DNA is seen as the string.
Final answer
(B) Nucleosome
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