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Question

The best method for the preparation of 2,2-dimethylbutane is via the reaction of:

A
Me3CBr and MeCH2Br in Na/ether
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B
(Me3C)2CuLi and MeCH2Br
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C
(MeCH2)2CuLi and Me3CBr
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D
Me3CMgI and MeCH2I
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Solution

The correct option is B (Me3C)2CuLi and MeCH2Br
2,2-dimethyl butane is prepared from Corey-House alkane synthesis

(Me3C)2CuLi+MeCH2BrSN2Me3CCH2CH3+BrMe3CCuLi

So, the correct option is B

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